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Figure 6 | Veterinary Research

Figure 6

From: Xanthohumol inhibits PRRSV proliferation and alleviates oxidative stress induced by PRRSV via the Nrf2–HMOX1 axis

Figure 6

Xanthohumol treatment upregulates the Nrf2 antioxidative pathway. A Heat map of expressed Nrf2 antioxidant genes modulated by 10 µM Xn or DMSO treatment in Marc-145 cells. Red and blue correspond to relative up- and downregulation, respectively. BH qRT-PCR quantification of the expression levels of Nrf2-regulated genes at four time points after 10 µM Xn treatment. The qRT-PCR was repeated at least three times, with each experiment performed in triplicate. ****P < 0.0001; ***P < 0.001; **P < 0.01; *P < 0.05 vs DMSO-treated cells for each time point

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