Figure 10
Xanthohumol suppresses oxidative stress induced by PRRSV in PAMs. A ROS generation in PAMs was determined using flow cytometry. The frequency of the cells that tested FITC positive among the total cells is shown in the lower right corner of the image. The histogram was used to quantify the number of FITC-positive cells in two independent trials. B–D Effects of 10 µM Xn on the levels of SOD, MDA, and GSH in PAMs infected with PRRSV or treated with H2O2. All results are means ± standard deviations from three independent experiments performed in triplicate. ###P < 0.001; ##P < 0.01; #P < 0.05 vs H2O2-treated group. ***P < 0.001; **P < 0.01; *P < 0.05 vs PRRSV-infected cells