Skip to main content

Table 5 Clinical signs and gross lesions observed at pm 43 days post-challenge with the cocktail in the caecum and colon of pigs in experiment 2

From: An atypical weakly haemolytic strain of Brachyspira hyodysenteriae is avirulent and can be used to protect pigs from developing swine dysentery

Pig group

Pig number

Clinical signsa

Lesions observed at pmb

Culturec

Caecum

Colon

Caecum

Colon

Faeces

A

1

0

[0]

[0]

0

0

0

2

0

[0]

[0]

0

0

0

3

0

[0]

[0]

0

0

0

4

0

[0]

[0]

0

0

0

6

0

[0]

[0]

0

0

0

7

0

[0]

[0]

0

0

0

10

0

[0]

[0]

0

0

0

15

0

[0]

[0]

0

3e

0

16

0

[0]

[0]

0

1e

0

18

0

[0]

[0]

0

1e

0

22

0

[0]

[0]

0

3e

0

26

0

[0]

[0]

0

0

0

Mediand

 

0

0

0

0

0

0*

B

5

0

[0]

[0]

0

0

0

9

0

[0]

[0]

0

5

3

12

3

[3]

[4] (entire length)

0

5

5

14

1

[0]

[3] (upper 1/3)

0

5

3

19

0

[0]

[0]

0

5

5

23

0

[0]

[2] (upper 1/3)

0

5

2

24

0

[0]

[2] (upper 1/3)

0

5

3

25

0

[0]

[0]

0

5e

5e

27

0

[0]

[0]

0

0

0

29

0

[0]

[0]

0

0

0

32

0

[0]

[0]

0

0

0

33

0

[0]

[0]

0

0

0

Mediand

 

0##

0

0##

0##

5

2.5*#

C

8

3

[1]

[4] (plus fibrin, entire length)

4

5

5

11

1

[0]

[3] (upper 1/3)

0

5

5

13

1

[0]

[3] (upper 1/3)

2

5

5

17

3

[4]

[4] (plus fibrin, entire length)

5

5

5

20

3

[4]

[4] (plus fibrin, entire length)

5

5

5

21

3

[4]

[4] (plus fibrin, entire length)

5

5

5

28

3

[0]

[4] (plus fibrin, entire length)

3

5

5

30

3

[4]

[4] (plus fibrin, entire length)

5

5

5

31

3

[0]

[4] (plus fibrin, entire length)

5

5

5

34

3

[1]

[4] (entire length)

5

5

5

35

0

[0]

[0]

0

0

0

36

0

[0]

[0]

0

5

1

Mediand

 

3##

0.5

4##

4.5##

5

5#

  1. Group A was experimentally inoculated with weakly haemolytic B. hyodysenteriae strain MU1. Group B was inoculated with MU1 and subsequently challenged with a mixture of five virulent field strains of B. hyodysenteriae. Group C was only challenged with the virulent strains.
  2. aClinical signs: 0, normal; 1, diarrhoea; 2, diarrhoea with mucus; 3, dysentery.
  3. bLesion scores: [0] normal; [1] mild localised erythema; [2] mild superficial erosions; [3] moderate superficial erosions; [4] severe erosions with mucus and fresh blood.
  4. cCulture score: 1 to 5, extent of growth on selective agar plates; 0, no growth.
  5. dMedians for groups A and B that were significantly different in a Mann–Whitney test are marked with an asterisk (* p = 0.05). Medians for groups B and C that were significantly different in a Mann–Whitney test are marked with hashes (#p < 0.05; ##p < 0.01).
  6. eGrowth of weakly haemolytic B. hyodysenteriae (MU1). All others were strongly haemolytic.