Table 2 Difference of miRNAs cluster targets enrichment between female and male
Gender | Stages | Specific functional enrichments |
|---|---|---|
Female | Cluster 1 (pairing stage) | Regulation of chemotaxis Leukocyte proliferation Cell junction organization Regulation of epithelial to mesenchymal transition |
Cluster 2 (developmental and mature stage) | Response to BMP (bone morphogenetic protein) Female pregnancy Spermatid differentiation Regulation of meiotic cell cycle | |
Cluster 3 (egg production stage) | Nerve development Chemosensory behavior | |
Male | Cluster 1 (pairing stage) | Sex differentiation Meiotic nuclear division |
Cluster 2 (developmental and mature stage) | Regulation of immune effector process Regulation of cell growth Regulation of response to biotic stimulus | |
Cluster 3 (egg production stage) | Cell communication by chemical coupling Regulation of cholesterol homeostasis Regulation of protein activation cascade Body morphogenesis |