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Figure 8 | Veterinary Research

Figure 8

From: Nuclear localization of Newcastle disease virus matrix protein promotes virus replication by affecting viral RNA synthesis and transcription and inhibiting host cell transcription

Figure 8

The schematic diagram of the replication and transcription of NDV genome and the potential functions of M protein in the nucleus. Transcription and replication of the NDV genome occurs in the cytoplasm by the action of viral RNP. During the course of NDV infection, the M protein is localized in the nucleus early in infection and enters the cytoplasm and binds to the cellular membrane later in infection. The potential functions of M in the nucleus are indicated according to our findings.

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