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Figure 1 | Veterinary Research

Figure 1

From: Nuclear localization of Newcastle disease virus matrix protein promotes virus replication by affecting viral RNA synthesis and transcription and inhibiting host cell transcription

Figure 1

Nuclear localization of M protein promotes the cytopathogenicity of NDV. The subcellular localizations of M protein in DF-1 cells infected with rSS1GFP or rSS1GFP-M/NLSm were examined by immunofluorescence staining (A) and Western blotting (B). The relative levels of the M protein were compared with the control Lamin B1 or Tubulin expression. N represents the nucleus and C represents the cytoplasm. C The CPE and GFP expression were observed in rSS1GFP- or rSS1GFP-M/NLSm-infected DF-1 cells at the indicated time points. Original magnification was 1 × 200. D The syncytium formation in plasmids-transfected DF-1 cells. The number of syncytia (cells containing more than three nuclei) was counted in 10 random areas of the well (mean ± SD).

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Veterinary Research

ISSN: 1297-9716