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Figure 1 | Veterinary Research

Figure 1

From: Role of p53 in pseudorabies virus replication, pathogenicity, and host immune responses

Figure 1

Effect of p53 on the PRV replication in vitro. A The viral gB gene copies were detected in PFT-α (p53 inhibitor) treated PK-15 pCDH-p53, PK-15 pCDH-p53 and PK-15 pCDH cells after 0.1 MO PRV infection in 4, 8, 12, and 24 h by quantitative real-time PCR. B Titers of PRV were determined in PFT-α treated PK-15 pCDH-p53, PK-15 pCDH-p53 and PK-15 pCDH cells after 0.1 MO PRV infection in 4, 8, 12, and 24 h by TCID50. C The viral gB gene copies were detected in PFT-α treated PK-15 and mock PK-15 cells after 0.1 MO PRV infection in 4, 8, 12, and 24 h by quantitative real-time PCR. D Titers of PRV were determined in PFT-α treated PK-15 and mock PK-15 cells after 0.1 MO PRV infection in 4, 8, 12, and 24 h by TCID50. All the results were confirmed by three independent experiments. Error bars represent the standard deviations of triplicate experiments. *P < 0.05; **P < 0.01.

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