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TableĀ 1 Significantly over-represented regulators in clusters D, E, and F

From: Regulators of Salmonella-host interaction identified by peripheral blood transcriptome profiling: roles of TGFB1 and TRP53 in intracellular Salmonella replication in pigs

Cluster name Pathway regulator Gene count in pathway Gene count in cluster P0a P1b FDRc
Cluster D Egf 459 8 0.084 0.364 0.000
Cluster D Mapk1 528 6 0.096 0.273 0.013
Cluster D Ppara 255 5 0.046 0.227 0.003
Cluster D Mapk3 283 5 0.052 0.227 0.004
Cluster D Lep 295 5 0.054 0.227 0.005
Cluster D Mapk14 386 5 0.070 0.227 0.014
Cluster D Trp53 405 5 0.074 0.227 0.016
Cluster D Il4 446 5 0.081 0.227 0.025
Cluster D Il6 478 5 0.087 0.227 0.031
Cluster E Tnf 1061 17 0.193 0.370 0.003
Cluster E Tgfb1 966 15 0.176 0.326 0.007
Cluster E Fgf2 397 8 0.072 0.174 0.015
Cluster E Il4 446 8 0.081 0.174 0.024
Cluster E Creb1 247 7 0.045 0.152 0.005
Cluster E Bdnf 123 6 0.022 0.130 0.001
Cluster E Ifnb1 168 6 0.031 0.130 0.003
Cluster E Cd8a 159 6 0.029 0.130 0.003
Cluster E Hgf 237 6 0.043 0.130 0.013
Cluster E Il2 245 6 0.045 0.130 0.015
Cluster E Notch1 255 6 0.046 0.130 0.016
Cluster E Csf2 249 6 0.045 0.130 0.019
Cluster E Sirt1 89 5 0.016 0.109 0.001
Cluster E Pten 102 5 0.019 0.109 0.002
Cluster E Csf3 127 5 0.023 0.109 0.005
Cluster E Src 188 5 0.034 0.109 0.017
Cluster E Edn1 188 5 0.034 0.109 0.021
Cluster E Egfr 218 5 0.040 0.109 0.034
Cluster E Bmp4 197 5 0.036 0.109 0.035
Cluster E Vegfa 250 5 0.046 0.109 0.043
Cluster F Trp53 405 14 0.074 0.128 0.017
Cluster F Mapk14 386 13 0.070 0.119 0.027
Cluster F Cd8a 159 7 0.029 0.064 0.047
Cluster F Gata1 88 5 0.016 0.046 0.031
  1. aAn expected ratio in the background.
  2. bAn observed ratio in the list of differentially expressed gene.
  3. cStatistical analysis was performed based on cumulative hypergeometric distribution and corrected by Benjamini and Hochberg method.