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Table 2 Transmission of Sh294 to TgOvPrP59 mice

From: Interspecies transmission to bovinized transgenic mice uncovers new features of a CH1641-like scrapie isolate

Source Recipient Passage # Survival perioda PrPresb
Brain Spleen
Sh294 brain (CH1641-like scrapie) TgOvPrP59 1 259 ± 24.5 10/10 0/10
2 233 ± 13.4 5/5 0/5
3 215 ± 17.9 5/5 0/5
  1. aSurvival periods are shown as mean survival days ± standard deviation.
  2. bThe number of analyzed mice is shown together with the results of PrPres detection in the brain and spleen (number of PrPres-positive mice/number of inoculated mice). All mice showed clinical signs of disease, such as clasping.