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Figure 5 | Veterinary Research

Figure 5

From: Interspecies transmission to bovinized transgenic mice uncovers new features of a CH1641-like scrapie isolate

Figure 5

PrPd distribution in the brains of ICR mice infected with TgBo-passaged Sh294. Sections of the hippocampus and thalamus were subjected to immunostaining for PrPd AC and GFAP C. Granular PrPd was dispersed in neuronal cells, glial cells (arrows), and neuropils A, B. Some PrPd signals were detected in the cytoplasm of hypertrophied astrocytes (yellow) C. Scale bars indicate 50 µm A, B and 10 µm C.

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