Predicted size of the pan-genome of M. hyopneumoniae. A Comparative overview of the pan-genome and core genome of M. hyopneumoniae. The M. hyopneumoniae pan-genome is shown in green (1152 genes), while the core genome is shown in orange (481 genes). Each plot point represents the mean value for gene clusters in the respective number of genomes, and curves represent power law fitting of the data. B Flower-plot schematic diagram of all nine M. hyopneumoniae strains for which genome data are available, showing the core genome size (flower centre) and the number of unique genes for each strain (flower petals). Numbers below the name of each strain indicate the total number of genes.