|
Group
|
Animal n°
|
Viremic day
|
Viral load
|
π
|
Difference between donor and recipient
|
Difference between consecutive samples
|
|---|
|
Inoculum produced in PAM
|
N.A.
| | |
0.0127
| | |
|
Inoculated animals
|
D1
|
1
|
7.91E+06
|
0.0045
|
−0.0082
| |
|
6
|
6.04E+05
|
0.0182
| |
+0.0137
|
|
13
|
6.18E+06
|
0.0239
| |
+0.0057
|
|
D2
|
1
|
1.24E+05
|
0.0091
|
−0.0036
| |
|
6
|
3.23E+05
|
0.0124
| |
+0.0033
|
|
13
|
1.24E+05
|
0.0115
| |
−0.0009
|
|
D3
|
1
|
1.07E+06
|
0.0064
|
−0.0063
| |
|
13
|
1.15E+07
|
0.0075
| |
+0.0011
|
|
D4
|
6
|
3.46E+05
|
0.0117
|
−0.0010
| |
|
13
|
2.14E+06
|
0.0528
| |
+0.0411
|
|
D5
|
1
|
1.11E+06
|
0.0123
|
−0.0004
| |
|
13
|
6.09E+05
|
0.0132
| |
+0.0009
|
|
6
|
1
|
5.66E+05
|
0.0305
|
+0.0178
| |
|
6
|
1.40E+07
|
0.0308
| |
+0.0003
|
|
15
|
1.97E+05
|
0.0097
| |
−0.0211
|
|
7
|
1
|
3.60E+06
|
0.0072
|
−0.0055
| |
|
13
|
5.88E+05
|
0.0524
| |
+0.0452
|
|
8
|
1
|
5.71E+05
|
0.0064
|
−0.0063
| |
|
06
|
7.37E+04
|
0.0152
| |
+0.0088
|
|
13
|
2.66E+06
|
0.0088
| |
−0.0064
|
|
9
|
1
|
4.81E+06
|
0.0091
|
−0.0036
| |
|
6
|
2.58E+05
|
0.0041
| |
−0.0050
|
|
13
|
1.64E++06
|
0.0335
| |
+0.0294
|
|
Naïve infected by contact
|
R1
|
1
|
1.23E+07
|
0.0031
|
−0.0151
| |
|
6
|
4.60E+04
|
0.0119
| |
+0.0088
|
|
22
|
5.99E+03
|
0.0178
| |
+0.0059
|
|
R2
|
1
|
1.63E+06
|
0.0108
|
−0.0090
| |
|
8
|
2.41E+07
|
0.0091
| |
−0.0017
|
|
15
|
2.25E+03
|
0.0109
| |
+0.0018
|
|
R3
|
3
|
2.76E+05
|
0.0134
|
+0.007
| |
|
10
|
8.57E+06
|
0.0165
| |
−0.0031
|
|
R4
|
1
|
3.17E+06
|
0.0092
|
−0.0025
| |
|
5
|
2.90E+08
|
0.0065
| |
+0.0027
|
|
R5
|
3
|
6.06E+06
|
0.0069
|
−0.0054
| |
|
10
|
5.97E+06
|
0.0099
| |
+0.0030
|
- The table shows the difference in nucleotide diversity between: (i) the transmissible population in sera for the donor before the transmission and the founders in the recipient at the first day of viremia, and (ii) samples of the same animals in different days of the virological course. The difference of nucleotide diversities was calculated by subtracting the π value of a given day from the π value the previous examined day. For the first day of each animal the difference was calculated with regards to the inoculum (inoculated animals) or with regards to the diversity of the donor (D1 to D5) on the likely day of transmission (transmission by contact) to the corresponding recipient (R1 to R5) animals. In italic, the most likely day of transmission for the donor animals.
