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Table 1 Variation of the viral load and nucleotide diversity (π) in transmission events and between days of viremia

From: Bottlenecks in the transmission of porcine reproductive and respiratory syndrome virus (PRRSV1) to naïve pigs and the quasi-species variation of the virus during infection in vaccinated pigs

Group Animal n° Viremic day Viral load π Difference between donor and recipient Difference between consecutive samples
Inoculum produced in PAM N.A.    0.0127   
Inoculated animals D1 1 7.91E+06 0.0045 −0.0082  
6 6.04E+05 0.0182   +0.0137
13 6.18E+06 0.0239   +0.0057
D2 1 1.24E+05 0.0091 −0.0036  
6 3.23E+05 0.0124   +0.0033
13 1.24E+05 0.0115   −0.0009
D3 1 1.07E+06 0.0064 −0.0063  
13 1.15E+07 0.0075   +0.0011
D4 6 3.46E+05 0.0117 −0.0010  
13 2.14E+06 0.0528   +0.0411
D5 1 1.11E+06 0.0123 −0.0004  
13 6.09E+05 0.0132   +0.0009
6 1 5.66E+05 0.0305 +0.0178  
6 1.40E+07 0.0308   +0.0003
15 1.97E+05 0.0097   −0.0211
7 1 3.60E+06 0.0072 −0.0055  
13 5.88E+05 0.0524   +0.0452
8 1 5.71E+05 0.0064 −0.0063  
06 7.37E+04 0.0152   +0.0088
13 2.66E+06 0.0088   −0.0064
9 1 4.81E+06 0.0091 −0.0036  
6 2.58E+05 0.0041   −0.0050
13 1.64E++06 0.0335   +0.0294
Naïve infected by contact R1 1 1.23E+07 0.0031 −0.0151  
6 4.60E+04 0.0119   +0.0088
22 5.99E+03 0.0178   +0.0059
R2 1 1.63E+06 0.0108 −0.0090  
8 2.41E+07 0.0091   −0.0017
15 2.25E+03 0.0109   +0.0018
R3 3 2.76E+05 0.0134 +0.007  
10 8.57E+06 0.0165   −0.0031
R4 1 3.17E+06 0.0092 −0.0025  
5 2.90E+08 0.0065   +0.0027
R5 3 6.06E+06 0.0069 −0.0054  
10 5.97E+06 0.0099   +0.0030
  1. The table shows the difference in nucleotide diversity between: (i) the transmissible population in sera for the donor before the transmission and the founders in the recipient at the first day of viremia, and (ii) samples of the same animals in different days of the virological course. The difference of nucleotide diversities was calculated by subtracting the π value of a given day from the π value the previous examined day. For the first day of each animal the difference was calculated with regards to the inoculum (inoculated animals) or with regards to the diversity of the donor (D1 to D5) on the likely day of transmission (transmission by contact) to the corresponding recipient (R1 to R5) animals. In italic, the most likely day of transmission for the donor animals.