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Figure 6 | Veterinary Research

Figure 6

From: Inhibition of Salmonella Typhimurium adhesion, invasion, and intracellular survival via treatment with methyl gallate alone and in combination with marbofloxacin

Figure 6

Downregulation of Salmonella Typhimurium virulence genes by methyl gallate (MG). A Effect of MG on rac-1 expression, B effect of MG on cheY expression, C effect of MG on ompD expression, D effect of MG on sipB expression, E effect of MG on lexA expression, and F effect of MG on ompF expression. Bacteria were cultured with MG at different concentrations and incubated for 13 h in a non-shaking incubator aerobically at 37 °C. Gene expression levels were quantified via quantitative reverse transcription polymerase chain reaction. Control, inoculated with Salmonella Typhimurium but left untreated; MG-_100, inoculated with Salmonella Typhimurium and treated with 100 µg/mL of MG; MG_30, inoculated with Salmonella Typhimurium and treated with 30 µg/mL of MG; MGM, inoculated with Salmonella Typhimurium and treated with the combination of MG (30 µg/mL) and sub-MIC of MRB; Sub-MIC, inoculated with Salmonella Typhimurium and treated with sub-MIC of MRB. Values indicated are the mean ± SEM (n = 3; ***P-value < 0.001).

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