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Table 2 Mortality and bacterial load in the chickens post-challenge

From: Salmonella Gallinarum delivering M2eCD40L in protein and DNA formats acts as a bivalent vaccine against fowl typhoid and H9N2 infection in chickens

Groupsa Challengeb Livere Spleene
Mortalityc Liverd Spleend
PBS 6/8* 2/2* 2/2* 3.44 ± 2.42* 2.8 ± 1.84*
JOL916 1/8 4/7 0/7 2.88 ± 2.13 0
JOL2074 1/8 5/7 1/7 2.92 ± 2.20 0.75 ± 1.17
JOL2074 + JOL2076 1/8 4/7 0/7 2.75 ± 2.09 0
  1. aFour weeks old chickens (n = 8) were orally vaccinated with PBS, JOL916, JOL2074 or JOL2074 + JOL2076.
  2. bChallenge was performed with a wild-type SG strain using 1.6 × 106 CFU/bird after 28 days post-vaccination.
  3. cNumber of dead birds upon challenge.
  4. dNumber of birds positive for SG.
  5. eBacterial load in liver (CFU/gram) and spleen (CFU/spleen). *p < 0.05.