Figure 8

Photomicrographs of hematoxylin-and eosin-stained lung sections of chickens on 7^th day post-H9N2 challenge. Chickens (N = 10) were vaccinated with JOL2068, JOL2074 or JOL2074 + JOL2076, and 28 days later all the vaccinated chickens were challenged with 10⁵ TCID₅₀ H9N2 virus. At 7^th day post-challenge, chickens (n = 4) were sacrificed and lung tissues were collected for histological analysis. Chickens that received JOL2068 showed hyperemia with infiltration of mononuclear inflammatory cells in bronchi and lung parenchyma, while as vaccinated birds showed minimum inflammatory lesions. Arrows indicate inflammatory lesions. The experiment was repeated twice and the results are shown of one independent experiment.