Oral immunization with a novel attenuated Salmonella Gallinarum encoding infectious bronchitis virus spike protein induces protective immune responses against fowl typhoid and infectious bronchitis in chickens

Table 2 Protective efficacy of orally administered SG-based S1 vaccine (JOL2077) in brown nick layer chickens

Groups	Recovery of virus from trachea No. positive/no. tested	% protection^a
PBS	6/6	0
JOL2068	6/6	0
JOL2077	2/6	66.7

Chickens were challenged with virulent IBV strain nasally at 4 weeks post-vaccination. The challenged virus was isolated from the trachea at 6^th day post-challenge and the immunoprotection efficacy was assayed.
^aPercent protection was determined as the number of positive chickens/total number of chickens.

ISSN: 1297-9716