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Table 4 The top proteins with the largest change in expression in response to ASFV infection (7 dpi)

From: Comparative proteomic analysis reveals different responses in porcine lymph nodes to virulent and attenuated homologous African swine fever virus strains

  Attenuated-control
ID SSP ID Gen name Protein name pI Mw (kDa) % coverage Fold change p value
1509 Q0QEM6 ATP5B ATP synthase subunit beta Sus scrofa 4.99 47.10 72 26.6 0.0236
1405 F8VYX6 TUBB Tubulin beta chain Homo sapiens 5.1 48.90 37 9.1 0.0222
8512 F1RFI1 TUFM Elongation factor Tu Sus scrofa 6.72 49.70 46 6 0.0004
8606 P01790 IGH Ig heavy chain V region Mus musculus 8.01 13.70 24 5.7 0.0232
1612 P02543 VIM Vimentin Sus scrofa 5.06 53.70 57 4.5 0.0097
3319 B4DWA6 CAPZB Highly similar to F-actin capping protein subunit beta Homo sapiens 5.77 37.8 31 4.1 0
4005 Q2TBX5 SSR4 Translocon-associated protein subunit delta Bos taurus 5.49 19.00 37 3.9 0.095
7412 Q9GKX6 GALM Aldose 1-epimerase Sus scrofa 6.31 38.00 30 3.7 0.0044
8209 B5APU7 ARPC2 Actin-related protein 2/3 complex subunit 2 Sus scrofa 6.84 34.3 63 3.7 0.025
7108 D6RBM0 HNRNPH1 Heterogeneous nuclear ribonucleoprotein H Homo sapiens 6.97 24.2 62 3.7 0.0033
3005 B3KWQ3 ACTG Highly similar to Actin. cytoplasmic 2 Homo sapiens 5.2 28.50 29 − 12 0.0055
7309 F1RUN2 ALB Serum albumin Sus scrofa 5.98 71.60 30 − 5 0.0004
3720 Q5T6W5 HNRNPK Heterogeneous nuclear ribonucleoprotein K Homo sapiens 5.46 47.70 41 − 4.9 0.018
1308 A5D989 EEF1D Elongation factor 1-delta Bos taurus 4.94 31.2 27 − 4.8 0
3723 F1MUZ9 HSPD1 60 kDa chaperonin Bos taurus 5.71 61.10 42 − 4.3 0.0017
3318 P11493| PPP2CB Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Homo sapiens 5.46 34.1 35 − 3.2 0.023
4112 Q1W2K3 PSMB10 Proteasome subunit beta Sus scrofa 6.09 29.20 23 − 3.2 0.0004
2613 F1RG16 HNRNPF Heterogeneous nuclear ribonucleoprotein F Sus scrofa 5.32 45.90 42 − 3.1 0.0452
305 I3L813 PCNA Proliferating cell nuclear antigen Sus scrofa 4.57 29.1 63 − 2.9 0.005
2309 G7P8A3 EGM_15385 Serine/threonine-protein phosphatase Macaca fascicularis 5.55 33.9 46 − 2.4 0.0003
  Virulent-control
ID SSP ID Gen name Protein name pI Mw (Kda) % coverage Fold change p value
3516 F1MRD0 ACTB Actin.cytoplasmic 1.Bos taurus 5.16 42.20 38 6.1 0.0255
7309 F1RUN2 ALB Serumalbumin Sus scrofa 5.98 71.60 30 − 26 0.011
3005 B3KWQ3 ACTG Highly similar to Actin. cytoplasmic 2 Homo sapiens 5.2 28.50 29 − 24 0.0214
6417 Q8IY98 ACTR2 Actin-related protein 2 Homo sapiens 5.77 39.90 43 − 6.4 0.0004
6313 O88550 CASP7 Caspase 7 Rattus norvegicus 5.53 34.9 17 − 5.5 0.0125
2012 Q0IIA3 SRI Sorcin Bos taurus 5.11 20.60 20 − 4.7 0.014
9012 Q9BGI4 PRDX1 Peroxiredoxin 1 Bos taurus 8.81 22.4 40 − 4.6 0.0013
3314 Q15181 PPA1 Inorganic pyrophosphatase Homo sapiens 5.54 33.1 41 − 4.4 0.0374
2613 F1RG16 HNRNPF Heterogeneous nuclear ribonucleoprotein F Sus scrofa 5.32 45.90 42 − 4.3 0.0357
207 P61981 YWHAG 14-3-3 protein gamma Homo sapiens 4.8 28.4 59 − 3.4 0.017
2309 G7P8A3 EGM_15385 Serine/threonine-protein phosphatase Macaca fascicularis 5.55 33.9 46 − 2.8 0.0223
6416 Q99LC3 NDUFA10 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10. Mus musculus 7.63 40.80 22 − 2.3 0.027
2208 F2Z5C1 ANXA5 Annexin Sus scrofa 4.95 33.2 59 − 2.1 0.0313
305 I3L813 PCNA Proliferating cell nuclear antigen Sus scrofa 4.57 29.1 63 − 2 0.0401
2108 F1SQW8 ARHGDIB Rho protein dissociation inhibitor homolog Sus scrofa 5.08 22.90 55 − 1.8 0.047
306 F1M0S3 TPM2 Tropomyosin beta chain Rattus norvegicus 5.19 31.1 40 − 1.8 0.0155
7213 K7D9V9 HNRNPH3 Heteroproteinous nuclear ribonucleoprotein H3 Pan troglodytes 6.36 35.2 68 − 1.7 0.0419