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Table 2 The top proteins with the largest change in expression in response to ASFV infection (1 dpi)

From: Comparative proteomic analysis reveals different responses in porcine lymph nodes to virulent and attenuated homologous African swine fever virus strains

  Attenuated-control
ID SSP ID Gen name Protein name pI Mw (kDa) % coverage Fold change p value
5605 F1RUN2 ALB Serum albumin Sus scrofa 5.98 71.60 19 34.7 0.0006
605 P02543 VIM Vimentin Sus scrofa 5.06 53.70 63 27.5 0.001
1307 Q6QAQ1 ACTB Actin.cytoplasmic 1 Sus scrofa 5.29 42.1 19 11 0.0002
6718 P02554 TUBB Tubulin beta chain Sus scrofa 4.78 50.30 17 10.1 0.0024
8411 I7GKE9 EEF2 Similar to human eukaryotic translation elongation factor Macaca fascicularis 5.93 36.4 21 6.7 0.002
4807 F1RMN7 HPX Hemopexin Sus scrofa 6.59 52.10 21 4.5 0.0003
8315 F1RS36 HSPA5 78 kDaglucose-regulated protein Sus scrofa 5.21 70.3 24 4.2 0.0175
8219 I3L816 HNRNPH1 Heterogeneous nuclear ribonucleoprotein H Sus scrofa 6.44 46.6 34 3.8 0.0014
8107 K7EJP1 ATP5A1 ATP synthase subunit alpha.mitochondrial Homo sapiens 5.51 15.40 29 3.5 0.0047
9602 I3LK59 ENO Enolase Sus scrofa 8.93 38.20 29 3.4 0.0005
4806 Q6S4N2 HSPA1B Heat shock 70 kDa protein 1B Sus scrofa 5.6 70.30 18 − 23.1 0
9508 I3LEC2 PCBP1 Poly(rC)-binding protein 1 Sus scrofa 6.66 37.9 39 − 15 0.0001
7420 F1RKU0 IDH3A Isocitrate dehydrogenase [NAD] subuni talpha, mitochondrial Sus scrofa 6.72 40.1 24 − 10 0.0105
407 F1M0S3 TPM2 Tropomyosin beta chain Rattus norvegicus 5.19 31.1 38 − 9.6 0.0003
502 C9J9K3 RPSA 40S ribosomal protein SA Homo sapiens 5.15 30 62 − 8.6 0.0001
302 P62258 YWHAE 14-3-3 protein epsilon Homo sapiens 4.79 29.2 44 − 7.5 0.0023
9804 P09571 TF Serotransferrin Sus scrofa 6.93 78.90 36 − 6.9 0.0013
9401 P00355 GAPDH Glyceraldehyde-3-phosphate dehydrogenase Sus scrofa 8.51 36.1 34 − 5.7 0.001
205 F2Z558 YWHAZ 14-3-3 protein zeta Sus scrofa 4.77 28.20 42 − 5.4 0.0032
9107 F1S3U9 PRDX1 Peroxiredoxin 1 Sus scrofa 8.67 22.1 44 − 5.1 0.0052
  Virulent-control
ID SSP ID Gen name Protein name pI Mw (kDa) % coverage Fold change p value
4107 F1RUN2 ALB Serum albumin Sus scrofa 5.98 71.60 5 13.4 0.0012
6718 P02554 TUBB Tubulin beta chain Susscrofa 4.78 50.30 17 11.3 0.0003
5411 F1RPH0 PGK1 Phosphoglycerate kinase Sus scrofa 6.32 43.4 30 7.3 0.0009
8214 D0G7F6 TPI1 Triosephosphate isomerase Sus scrofa 6.54 23.90 89 6.5 0.001
8411 I7GKE9 EEF2 Similar to human eukaryotic translation elongation factor Macaca fascicularis 5.93 36.4 21 6.5 0.0023
4308 B6VNT8 ACTC1 Alpha actin 1 Sus scrofa 5.23 42.3 8 5 0.0005
8107 K7EJP1 ATP5A1 ATP synthase subunit alpha.mitochondrial Homo sapiens 5.51 15.40 29 3.5 0.0002
8219 I3L816 HNRNPH1 Heterogeneous nuclear ribonucleoprotein H Sus scrofa 6.44 46.6 34 3.4 0.0008
1410 Q9N0Y9| TMOD3 Ubiquitous tropomodulin U-Tmod Sus scrofa 4.98 39.7 31 2.4 0.0002
7504 F1SVB0 CAPG Macrophage-capping protein Sus scrofa 5.88 39.2 23 2.3 0.0022
9107 F1S3U9 PRDX1 Peroxiredoxin 1 Sus scrofa 8.67 22.1 44 − 6.1 0.0009
302 P62258 YWHAE 14-3-3 protein epsilon Homo sapiens 4.79 29.2 44 − 13.6 0.0027
8806 P09571 TF Serotransferrin Sus scrofa 6.93 78.9 32 − 11.7 0.0001
301 Q5ISS9 YWHAQ 14-3-3 protein theta isoform Sus scrofa 4.7 29.20 49 − 11.4 0.0002
7715 F1RFN9 FSCN1 Fascin Sus scrofa 6.04 55.20 26 − 9.8 0.001
8404 A2A6G8 Lasp1 LIM and SH3 domain protein 1 Mus musculus 9.14 12.1 50 − 7.5 0.0004
8510 I3LDC7| IDH1 Isocitrate dehydrogenase [NADP] (Fragment) Sus scrofa 7.64 48.7 24 − 7 0.0011
407 F1M0S3 TPM2 Tropomyosin beta chain Rattus norvegicus 5.19 31.1 38 − 5.2 0.0007
502 C9J9K3 RPSA 40S ribosomal protein SA Homo sapiens 5.15 30 62 − 4.8 0.0002
5113 Q08024 CBFB Core-binding factor subunit beta Mus musculus 5.59 22.2 31 − 4.4 0.0008