Table 5 Differential expression profile of genes that positively regulate apoptosis in peritoneal exudate cells from cats with FIP compared to peritoneal cells from healthy cats. The list was modified from QIAGEN human apoptosis PCR array
Gene symbol | Description | Log2FC | P adjusted |
|---|---|---|---|
FAS | Fas cell surface death receptor | 4.44221 | 1.66E−19 |
CD70 | CD70 molecule | 3.91193 | 0.0008 |
TRAF2 | TNF receptor-associated factor 2 | 3.69038 | 2.77E−19 |
FASLG | Fas ligand (TNF superfamily, member 6) | 3.51023 | 0.00019 |
BAK1 | BCL2-antagonist/killer 1 | 3.41627 | 1.85E−17 |
TNF | Tumor necrosis factor | 3.15917 | 2.35E−15 |
TNFSF10 | Tumor necrosis factor (ligand) superfamily, member 10 | 3.10015 | 5.33E−15 |
BID | BH3 interacting domain death agonist | 2.46508 | 1.95E−09 |
CD27 | CD27 molecule | 2.30807 | 0.01807 |
BCL2L11 | BCL2-like 11 (apoptosis facilitator) | 2.25067 | 6.41E−06 |
CASP10 | Caspase 10, apoptosis-related cysteine peptidase | 2.12608 | 3.21E−08 |
CASP8 | Caspase 8, apoptosis-related cysteine peptidase | 2.00000 | 3.56E−07 |
BCL10 | B-cell CLL/lymphoma 10 | 1.49878 | 0.00021 |
CIDEA | Cell death-inducing DFFA-like effector a | 1.45359 | 0.26372 |
TNFSF9 | Tumor necrosis factor (ligand) superfamily, member 9 | 1.33377 | 0.00087 |
BRAF | B-Raf proto-oncogene, serine/threonine kinase | 1.27788 | 0.00326 |
DFFA | DNA fragmentation factor, 45Â kDa, alpha polypeptide | 0.92582 | 0.01018 |
BNIP3L | BCL2/adenovirus E1B 19Â kDa interacting protein 3-like | 0.84923 | 0.04892 |
BAX | BCL2-associated X protein | 0.77062 | 0.05153 |
BIK | BCL2-interacting killer (apoptosis-inducing) | 0.66673 | 0.28001 |
TRADD | TNFRSF1A-associated via death domain | −0.0058 | 0.96717 |
ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | −0.49077 | 0.19821 |
TP73 | Tumor protein p73 | −0.76667 | 0.17226 |
TP53BP2 | Tumor protein p53 binding protein 2 | − 0.76713 | 0.04169 |
TP53 | Tumor protein p53 | −0.99445 | 0.005241 |
CASP2 | Caspase 2, apoptosis-related cysteine peptidase | −1.18226 | 0.0037 |
DAPK1 | Death-associated protein kinase 1 | −1.59291 | 3.29E−06 |
NOD1 | Nucleotide-binding oligomerization domain containing 1 | −1.61573 | 3.08E−06 |
TNFSF8 | Tumor necrosis factor superfamily member 8 | −4.26451 | 7.28E−24 |