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Table 5 Differential expression profile of genes that positively regulate apoptosis in peritoneal exudate cells from cats with FIP compared to peritoneal cells from healthy cats. The list was modified from QIAGEN human apoptosis PCR array

From: Characterization of peritoneal cells from cats with experimentally-induced feline infectious peritonitis (FIP) using RNA-seq

Gene symbol Description Log2FC P adjusted
FAS Fas cell surface death receptor 4.44221 1.66E−19
CD70 CD70 molecule 3.91193 0.0008
TRAF2 TNF receptor-associated factor 2 3.69038 2.77E−19
FASLG Fas ligand (TNF superfamily, member 6) 3.51023 0.00019
BAK1 BCL2-antagonist/killer 1 3.41627 1.85E−17
TNF Tumor necrosis factor 3.15917 2.35E−15
TNFSF10 Tumor necrosis factor (ligand) superfamily, member 10 3.10015 5.33E−15
BID BH3 interacting domain death agonist 2.46508 1.95E−09
CD27 CD27 molecule 2.30807 0.01807
BCL2L11 BCL2-like 11 (apoptosis facilitator) 2.25067 6.41E−06
CASP10 Caspase 10, apoptosis-related cysteine peptidase 2.12608 3.21E−08
CASP8 Caspase 8, apoptosis-related cysteine peptidase 2.00000 3.56E−07
BCL10 B-cell CLL/lymphoma 10 1.49878 0.00021
CIDEA Cell death-inducing DFFA-like effector a 1.45359 0.26372
TNFSF9 Tumor necrosis factor (ligand) superfamily, member 9 1.33377 0.00087
BRAF B-Raf proto-oncogene, serine/threonine kinase 1.27788 0.00326
DFFA DNA fragmentation factor, 45 kDa, alpha polypeptide 0.92582 0.01018
BNIP3L BCL2/adenovirus E1B 19 kDa interacting protein 3-like 0.84923 0.04892
BAX BCL2-associated X protein 0.77062 0.05153
BIK BCL2-interacting killer (apoptosis-inducing) 0.66673 0.28001
TRADD TNFRSF1A-associated via death domain −0.0058 0.96717
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase −0.49077 0.19821
TP73 Tumor protein p73 −0.76667 0.17226
TP53BP2 Tumor protein p53 binding protein 2 − 0.76713 0.04169
TP53 Tumor protein p53 −0.99445 0.005241
CASP2 Caspase 2, apoptosis-related cysteine peptidase −1.18226 0.0037
DAPK1 Death-associated protein kinase 1 −1.59291 3.29E−06
NOD1 Nucleotide-binding oligomerization domain containing 1 −1.61573 3.08E−06
TNFSF8 Tumor necrosis factor superfamily member 8 −4.26451 7.28E−24
  1. Genes in italics were significantly up-regulated  and underlined genes significantly down-regulated.