Newcastle disease virus-attenuated vaccine LaSota played a key role in the pathogenicity of contaminated exogenous virus

Table 1 Animal experimental design

Groups	Vaccination methods	Vaccine	Vaccine dosage	Contaminated virus	Viral dosage	Chicken amount	Age/days
LaSota	Orally	NDV	A plume	No virus		15	7
PBS	Orally	PBS	A plume	No virus		15	7
LaSota/FAdV/CIAV/HD	Orally	NDV	A plume	FAdV + CIAV	50 EID₅₀ + 50 EID₅₀	15	7
LaSota/FAdV/CIAV/LD	Orally	NDV	A plume	FAdV + CIAV	10 EID₅₀ + 10 EID₅₀	15	7
PBS/FAdV/CIAV/HD	Orally	PBS	A plume	FAdV + CIAV	50 EID₅₀ + 50 EID₅₀	15	7
PBS/FAdV/CIAV/LD	Orally	PBS	A plume	FAdV + CIAV	10 EID₅₀ + 10 EID₅₀	15	7

H represents high dose, such as 50 EID₅₀; L represents low dose, such as 10 EID₅₀.

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