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Figure 4 | Veterinary Research

Figure 4

From: Endonuclease G takes part in AIF-mediated caspase-independent apoptosis in Mycobacterium bovis-infected bovine macrophages

Figure 4

Cyclosporine A treatment modifies the number of intracellular mycobacteria in bovine macrophages. Macrophages were infected with M. bovis AN5 (MOI 10:1) for 4 h to allow phagocytosis, washed to remove extracellular bacteria and cultured again for 24 h in the presence or absence of Cyclosporine A. Bacterial proportional growth was calculated by dividing the number of intracellular CFU at 24 h post-infection by the number of intracellular CFU at the end of phagocytosis and expressed as percentage. Values are mean ± standard deviation from two independent experiments each one with three internal replicas. Asterisk represents a p value equal or less than 0.05 of statistical significance.

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