Table 1 Candidate target genes for differentially expressed microRNA (miRNA) in PPRV- versus mock-infected goat PBMC

chi-miR-1

DOWN

0

TLR4, CD84, LOC108635363, LOC102182927, JKAMP, TNFRSF9, IL4R, TAL1, BMF, TRAF3, IFNGR1, IL2RG, TRAF5, HSPA13, IGSF10

chi-miR-143-3p

DOWN

1.86E−290

NECTIN4, IKBKG, IL4R

chi-miR-323a-3p

UP

6.59E−241

IRF3

chi-miR-485-5p

UP

1.06E−45

NECTIN4, LOC102182927, CSF2RB

chi-miR-1291

UP

6.33E−259

TMEM173, IFNAR1, TRADD, TCP11L1, CDON

novel_mir3

DOWN

0

SLAMF6, TMEM173, CCAR2, NECTIN4, PBX1, LOC108637844, IL17B, TRIL, GDF2, NFATC3, CD6, LOC106503960, BCL11A, LOC108635335, APAF1, IFRD1, ISLR2, TLR4, IL1RAP, HSPA2, IRF2BPL, NFKB2, IRAK1

novel_mir85

UP

0

IL1RAP, STAM2, TNFSF13B, TLR9

novel_mir218

DOWN

9.37E−14

IL23A, TAL2, INSIG1, CD82, SLAM

chi-miR-150

UP

0

LOC102172159, SLC13A4, IGFLR1, TLR6, RTP1, ITGB1

novel_mir70

UP

0

TLR4, JAM2, IL1RAP, HSPA2, MTOR, ITGAV, STAM2, TNFSF13B, TLR9

chi-miR-30b-3p

DOWN

4.26E−48

SRP19, IL22RA1, SOCS5, LOC102170232, LOC102178826, TMEM173, AREL1, IL18BP, IGF2BP3

novel_mir330

DOWN

1.09E−10

PBXIP1, SOCS2, ACKR1, TNIK, CD244, NCR1, LOC102182927, CASP8, ATG9A, TNIK

chi-miR-671-5p

UP

8.28E−63

CADM2, APAF1, TMEM173, IGF2

chi-miR-182

UP

8.31E−304

IL10, TNFRSF18, BCL11B, LOC106503930, BAX

chi-miR-155-3p

UP

4.01E−197

PBXIP1, NFKBIA