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Figure 7 | Veterinary Research

Figure 7

From: A Mycobacterium avium subsp. paratuberculosis relA deletion mutant and a 35 kDa major membrane protein elicit development of cytotoxic T lymphocytes with ability to kill intracellular bacteria

Figure 7

Flow cytometric analysis showing expression of newly synthesized perforin, GnzB in CD4, CD8 T cells. A Newly synthesized perforin was highly expressed in CD8 T cells from unvaccinated steers with low expression in CD4 T cells (right set of graphs). Newly synthesized perforin was below the limits of detection in primed mdPBMC incubated with uninfected MoMΦ (center set of graphs). B Expression of GnzB in infected MoMΦ was low in CD4 T cells. GnzB was present in approximately half of the CD8 T cells.

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Veterinary Research

ISSN: 1297-9716