Expression of intestinal epithelial cell lineage-specific genes in bovine small intestinal crypts and enteroids. A–H Heat maps showing the relative expression levels (log2 transcripts/million reads, TPM) of cell lineage-specific genes: A intestinal stem cell; B transit-amplifying (TA) cells, early enterocyte precursor (ECepr) cells, late enterocyte precursor (EClpr) cells; C enterocytes; D SL, secretory lineage; E goblet cells; F Paneth cells; G enteroendocrine precursor (EEpr) cells, enteroendocrine (EE) cells, enteroendocrine cell derived hormones; H tuft cells. P, enteroid passage number; ***α-defensin genes are not represented in the bovine genome. I Expression of POU2F3 in mRNA-seq data sets derived from distinct regions of the sheep gastrointestinal tract . N, neonate; L1, 1 week old lamb; L8, 8 week old lamb; A, adult.