Serum IgG antibody titers against S. suis cps7 ST29 strain 13-00283-02 increase between 4.5 and 10.5 weeks of age in 9 randomly selected, healthy piglets from a herd known to be infected with S. suis cps7, cps2 and cps9. IgG antibody titers of the 9 piglets were determined in sera every 2 weeks between 4.5 and 10.5 weeks of life. Titers rose significantly from 4.5 to 8.5 and 10.5 weeks of age. Means and standard deviations are indicated by horizontal lines and error bars, respectively. Significant differences were determined using one-way ANOVA with a consecutive Dunn’s multiple comparisons test. Significances are indicated (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001).