Animal age/breed | Infection status | Tissue used for study | Nematode species | Genes a | Technique | Study |
---|---|---|---|---|---|---|
Yearling Scottish Blackface sheep | Challenged naive sheep | Abomasal mucosa | T. circumcincta | ITLN2, IL4, galectin 14 | RT-PCR, Western blot | [9] |
Yearling sheep | Immune day 5 vs naïve day 5 | Abomasal mucosa | T. circumcincta | CLCA1, PDZK1IP1 | cDNA microarray, RT-PCR, QT-PCR | [37] |
Yearling sheep | Naive sheep | Abomasal mucosa | T. circumcincta | ITLN2, ITLN1, ITLN3 galectin 4, galectin 1 | cDNA microarray, RT-PCR, QT-PCR | [37] |
Yearling sheep | Naive day 5 vs naive day 0 | Abomasal mucosa | T. circumcincta | LYZ, MMP13 | cDNA microarray, RT-PCR, QT-PCR | [37] |
6 months old Merino-cross wethers | Infected sheep | Abomasal mucosa | H. contortus | ITLN2, CLCA1, interleukins | Sequential microarray (across all arrays) | [12] |
6 months old Merino-cross wethers | Infected sheep | Abomasal mucosa | H. contortus | ALPL, PDZK1IP1 | Sequential microarray (day 22 vs day 3 biopsies) | [12] |
Lambs | Primary challenge vs Tertiary challenge | Lymph node | T. colubriformis | PPARG, KRT5, SLC31A2, KRT18 | micro array data, QT PCR | [13] |
Lambs | Resistant sheep | Abomasal mucosa | T. colubriformis, H. contortus | DUOX1, IL2RA, IL10 | RT-PCR | [11] |
Adult sheep | Immune sheep | Abomasal mucosa | T. circumcincta | LYZ, ITLN2, ITLN3, CLCA, KRT10, KRT8, KRT19 | SDS-PAGE and Shortgun proteomics | [44] |
Lambs Scottish Blackface | Susceptible sheep | Lymph node | T. circumcincta | SLC30A2, galectin 14 | RNA-seq | [14] |
1 year old canaria hair breed (CHB) and canaria sheep (CS) | Infected CHB | Abomasal mucosa | H. contortus | galectin 15, IL5, ALPL, MMP1, MMP11, MMP14, MMP2 | RNA-seq, RT-PCR | [15] |
1 year old canaria hair breed (CHB) and canaria sheep (CS) | Infected CHB and CS | Abomasal mucosa | H. contortus | SLC2A3, IL1RL1 | RNA-seq, RT-PCR | [15] |
Lambs Scottish Blackface | Resistant vs Control | Lymph node | T. circumcincta | IL5RA, IL13, IL13RA2, IL1RL1, IL4, SLC9A4 | cDNA microarray, RT-PCR | [20] |
Lambs (Scottish Blackface x Leicester) | Infected sheep | Abomasum, lymph node | T. circumcincta | ITLN2, ITLN1, ITLN3 | Semi-quantitative RT-PCR | [10] |