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Figure 1 | Veterinary Research

Figure 1

From: Atrophy of primary lymphoid organs induced by Marek’s disease virus during early infection is associated with increased apoptosis, inhibition of cell proliferation and a severe B-lymphopenia

Figure 1

Thymus and bursa atrophy induced by the vvMDV RB-1B strain in White Leghorn B19/B19 chicks. A Organ weight/body weight ratios in CTL and MDV-infected chicks at 6, 10 and 14 dpi. The median is represented as a black line. Thymus and bursa relative weights were reduced significantly from 6 to 10 dpi respectively, in the MDV-infected group compared to the CTL group. B Histological structure of the thymus and the bursa at 10 dpi. Formalin-fixed tissues embedded in paraffin were sectioned and stained with HES. For the thymus, the cortex thickness (double-end arrow) was highly reduced in MDV-infected chicks (b) compared to controls (a). For the bursa, a massive cell depletion was observed in the medulla of the follicles in MDV-infected chicks (d) compared to the controls (c). Bar, 50 µm

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Veterinary Research

ISSN: 1297-9716