Figure 4

Involvement of S. aureus-specific molecules in anti-S. aureus-induced growth inhibition. ELISA analyses and in vitro bacterial culture studies confirmed the bacterial specificity of growth inhibition induced by anti-S. aureus. A After absorption of anti-S. aureus with S. epidermidis, the S. aureus-specific antibody titer was slightly decreased compared with that of the original anti-S. aureus. In contrast, little reactivity of anti-S. aureus with S. epidermidis was detected after absorption. B Anti-S. aureus absorbed with S. epidermidis did not inhibit the growth of S. aureus. Three separate experiments were performed, and the data represent the mean ± standard error of the mean. The p values calculated using one-way or two-way factorial analyses of variance are ^#p < 0.05 or ***p < 0.001 and ****p < 0.0001, respectively.