Figure 2

Inhibition of the growth in culture of S. aureus in the presence of anti-S. aureus. The neutralizing effects in vitro of anti-S. aureus on the growth of cultures of S. aureus and E. coli. A Growth of S. aureus (BM1006 and SA003 was inhibited in the presence of anti-S. aureus, whereas the growth of E. coli (JM109) was not detectably inhibited. B The amount of uncoupled total IgG remained constant in the culture broth during the overnight culture of S. aureus (BM1006). In contrast, residual killed and live S. aureus-specific IgG titers gradually decreased during the overnight culture. C The anti-S. aureus that was used in the overnight culture of S. aureus did not inhibit bacterial growth when reused. Three separate experiments were performed, and the data represent mean ± standard error of the mean. The p values calculated using one-way or two-way factorial analyses of variance are ^#p < 0.05 and ^##p < 0.01 or *p < 0.05; **p < 0.01; ***p < 0.001; and ****p < 0.0001, respectively.