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Table 2 Histological changes in the spleen of MSP1a/OMP7/8/9 protein-immunized mice and controls mice

From: A hybrid protein containing MSP1a repeats and Omp7, Omp8 and Omp9 epitopes protect immunized BALB/c mice against anaplasmosis

 

LIVER

SPLEEN

Hydrotropic degeneration

White pulp hyperplasia

Periarteriolar hyperplasia

Follicular hyperplasia

95% CI

p

95% CI

p

95% CI

p

95% CI

p

Non-immunized vs. immunized

0.2695 to 1.731

**

−2.397 to −0.9361

**

−2.064 to −0.6028

**

−2.397 to −0.9361

**

Non-immunized vs. adjuvant

−0.7305 to 0.7305

ns

−0.7305 to 0.7305

ns

−0.7305 to 0.7305

ns

−1.397 to 0.06387

ns

  1. ns: not significant.
  2. ** p < 0.005.