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Figure 3 | Veterinary Research

Figure 3

From: The C3HeB/FeJ mouse model recapitulates the hallmark of bovine tuberculosis lung lesions following Mycobacterium bovis aerogenous infection

Figure 3

Development of Type I, II and III lesions in lung of C3HeB/FeJ mice over M. bovis course of infection. Each panel represents a lesion (H&E) obtained from individual representative C3HeB/FeJ mice euthanized at different time-points following M. bovis AF2122/97 intra-nasal infection. A–C Progression of Type I lesions from animals at day 35 (A), 42 (B) and 65 (C, “*”: caseous necrosis). D–G Progression of Type II lesions from animals at day 21 (D), 23 (E), 28 (F) and 37 (G, “*”: caseous necrosis). H–K Progression of Type III lesions from animals at day 21 (H), 28 (I), 42 (J) and 65 (K). Scale bars: 100 μm (A, B; DK); 200 μm (C).

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