Figure 5From: Synergistic effect of PB2 283M and 526R contributes to enhanced virulence of H5N8 influenza viruses in mice The frequency of residues at positions 283 and 526 in the PB2 of various subtypes of IAVs isolated from different hosts. Full-length PB2 sequences of IAVs isolated from avian, swine and human were obtained from the Influenza Sequences Database. Sequence alignment was performed by the Clustal W alignment method using the Megalign program. The percentage of the isolates possessing the indicated residues within each subtype was calculated and indicated by the colored area.Back to article page