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Table 1 Fecal consistency scores and fecal PEDV RNA shedding titers in original US PEDV-, S-INDEL PEDV-, and mock (control)-inoculated piglets post inoculation and after challenge with the original US PEDV virus

From: Cross protective immune responses in nursing piglets infected with a US spike-insertion deletion porcine epidemic diarrhea virus strain and challenged with an original US PEDV strain

  Mean fecal PEDV RNA shedding titers (SD) (log10 GE/mL) Mean fecal consistency scores (SD) Pig diarrhea rates (%)
Control S-INDEL Original US PEDV Control S-INDEL Original US PEDV Control S-INDEL Original US PEDV
DPI 1–7 ND 8.2b (1.1) 9.1a (1.0) 0c 1.7b (1.0) 2.4a (0.5) 0b 100a 100a
DPI 8–14 ND 7.8 (1.1) 8.2 (0.2) 0 0.3 (0.5) 0.8 (0.9) 0b 0b 28a
DPI 15–21 ND 6.7b (0.9) 8.1a (0.3) 0 0 0 0 0 0
DPC 1–7 8.7a (0.8) 6.0b (3.1) 6.2b (0.3) 1.2a (1.0) 1.1a (0.9) 0b 100a 81a 0b
  1. Fecal viral RNA shedding titers were determined by TaqMan real-time reverse transcription-PCR.
  2. Fecal consistency scores 0, 1, 2 and 3 correspond to normal, pasty, semi-liquid, and liquid feces, respectively, with scores of ≥ 2 corresponding to diarrhea.
  3. Values with different letters (a, b and c) differ significantly between groups (one-way ANOVA for means and Fisher’s Exact test for diarrhea rates, respectively. p < 0.05).
  4. SD: standard deviation, ND: not detectable.