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Table 4 Results of FCoV antigen immunohistochemistry and FCoV RT-qPCR for tissue from cats with FIP and cats without FIP

From: Limitations of using feline coronavirus spike protein gene mutations to diagnose feline infectious peritonitis

Tissue source RT-qPCR Immunohistochemistry Total
Negativea Positive
Cats with FIP
  Negative 16 7 23
Positive (relative copy number: median, range) 69 (1.2 × 103, 1.4 × 107 to 1.6) 132 (4.9 × 104, 1.2 × 108 to 1.2) 201
  Total 85 139 224
Cats without FIP
  Negative 162 0 162
Positive (relative copy number: median, range) 19 (16, 9.4 × 103 to 2.7) 0 19
  Total 181 0 181
  1. aThis includes 11 tissue samples with histopathological changes consistent with FIP, from cats definitively diagnosed with FIP based on analysis of additional tissue, but for which immunohistochemistry was negative (10 were positive for FCoV by RT-qPCR).