accumulation in lymphoreticular tissues of BSE infected goats. A Spleen of a clinical cattle BSE infected wt/wt goat, 26 mpi. Antibody Bar224, bar 50 µm. B Mesenterial lymph node of a clinical cattle BSE infected R/Q211 goat, 30 mpi. Antibody bar 224, bar 20 µm. C Tonsil of a clinical cattle BSE infected I/M142 goat. Antibody R145, bar 50 µm. In all samples a mild to moderate PrPD accumulation in follicles and in the sinus of the spleen can be seen.