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Table 4 List of proteins which decreased in abundance in heterophils in response to S. Enteritidis infection

From: Differential protein expression in chicken macrophages and heterophils in vivo following infection with Salmonella Enteritidis

Acc. no. Protein name Gene ID Fold ratio inf: noninf Fold ratio vac: noninf Function
F1P1U6 Myeloperoxidase MPO 0.013* 0.071* Oxidative burst
E1C677 Natural killer cell activator Gga.18306 0.026* 0.21* GO prediction: regulation of cytokine biosynthetic process
F1NJT3 Fibronectin FN1 0.11* 0.56 Binds components of extracellular matrix
F1NFQ7 Serine protease 57 PRSSL1 0.15* 0.37* Serine-type endopeptidase activity
P00698 Lysozyme C LYZ 0.16* 0.37* Antimicrobial peptide
H9L027 Cathepsin G CTSG 0.19* 0.30* Lysosomal cysteine protease
Q6QLQ5 Cathelicidin-1 CATHL1 0.20* 0.51 Bactericidal, fungicidal and immunomodulatory activity
F1NZ37 Cathepsin L1 CTSL1 0.22* 0.48* Controlling element of neutrophil elastase activity
P30374 Ribonuclease homolog RSFR 0.23* 0.51 Lysosomal cysteine protease
P27042 Lysozyme G LYG2 0.24* 0.60 Antimicrobial peptide
F2Z4L6 Serum albumin ALB 0.24* 0.67 Plasma carrier
P02789 Ovotransferrin OTFB 0.26* 0.55 Iron binding, immune response
F1NGT3 Matrix metallopeptidase 9 MMP9 0.26* 0.77 Degradation of the extracellular matrix
F1NVM1 G-protein coupled receptor 97 GPR97 0.27* 0.66 Regulates migration
Q2IAL7 Cathelicidin-2 CATHL2 0.31* 0.78 Antimicrobial peptide
Q2UZR2 Phosphoglucomutase 1 PGM1 0.35* 0.43* Glucose metabolic process
E1BZS2 Nucleosome assembly protein 1-like NAP1L1 0.36* 0.22* Chaperone for the linker histone
P08940 Myeloid protein 1 LECT2 0.37* 0.62 Chemotactic factor
R4GH86 Glutathione peroxidase GPX 0.41* 0.57 Protects organism from oxidative damage
F1NYH8 Ena/VASP-like protein EVL 0.42* 0.70 Regulators of the actin cytoskeleton and cell migration
  1. * Significantly different from the expression in heterophils from the non-infected chickens.