Table 2 Twenty most characteristic proteins for macrophages (Ma) compared to heterophils (Het)
Acc. no. | Protein name | Gene ID | ∆PSMa | Fold ratio Ma:Het | Response to the infection | Function |
|---|---|---|---|---|---|---|
M1XGZ4 | Macrophage mannose receptor 1 like | MRC1L | 993 | Only Ma | No | C-Type lectin |
P98157 | Low-density lipoprotein receptor-related protein 1 | LRP1 | 810 | Only Ma | No | Endocytic receptor |
P07583 | Galectin 1 | LGALS1 | 607 | Only Ma | No | Beta-galactoside-binding lectin |
P43233 | Cathepsin B | CTSB | 538 | 8.42 | Increase | Cysteine protease |
F1NZ86 | Heat shock 70 protein, mortalin | HSP70 | 508 | 5.30 | No | Chaperon |
P05122 | Creatine kinase B-type | CKB | 467 | 34.77 | No | Energy transduction |
F1NDD6 | LDL receptor related protein associated protein 1 | LRPAP1 | 374 | Only Ma | No | LDL receptors trafficking |
F1NIX4 | Trans-2-enoyl-CoA reductase | MECR | 356 | 33.16 | Increase | Fatty acid elongation |
F1P180 | Aspartate aminotransferase | GOT2 | 350 | 7.27 | No | Transaminase |
P13914 | Arylamine N-acetyltransferase | NAT3 | 350 | 23.92 | No | Conjugating enzyme |
H9KZK0 | Protein containing the scavenger receptor cysteine-rich (SRCR) domain | DMBT1L | 318 | Only Ma | No | Scavenger receptor |
E1BZF7 | Putative phospholipase B | PLB | 317 | 6.23 | No | Removing fatty acids from phospholipids |
Q6J613 | Invariant chain isoform p41 | Li | 312 | 6.87 | No | Chaperone |
F1P582 | Mitochondrial ubiquinol-cytochrome-c reductase complex core protein 2 | UQCR | 309 | 4.36 | No | Oxidative phosphorylation |
Q5ZMW1 | Aconitate hydratase, mitochondrial | ACO2 | 306 | 6.17 | No | TCA cycle |
F1NAC6 | Cytochrome b-c1 complex subunit 1 | UQCRC1 | 289 | 6.42 | No | Oxidative phosphorylation |
F6R1X6 | Lupus la protein | SSB | 288 | 6.90 | No | Protecting of 3′ poly(U) terminus of transcribed RNA |
E1BTT4 | Trifunctional enzyme subunit beta, mitochondrial | HADHB | 287 | 30.61 | Increase | β-Oxidation of fatty acids |
Q5ZMN3 | Prohibitin-2 | PHB2 | 282 | 10.52 | No | Not clear |
F1NJD6 | Guanine deaminase, cypin | GDA | 275 | Only Ma | No | Oxidizes hypoxanthine to xanthine |