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Table 1 Twenty most characteristic proteins of heterophils (Het) compared to macrophages (Ma)

From: Differential protein expression in chicken macrophages and heterophils in vivo following infection with Salmonella Enteritidis

Acc. no. Protein name Gene ID ∆PSMa Fold ratio Het:Ma Response to the infection Function
P28318 MRP126, calprotectin MRP126 7170 9.07 No Calcium and zinc binding
P08940 Myeloid protein 1 LECT2 5532 6.32 Decrease Chemotactic factor for Het
P02789 Ovotransferrin OTFB 2351 4.87 Decrease Iron binding, immune response
O73790 Heterochromatin-associated protein MENT SERPINB10 1760 6.00 No DNA condensation, cysteine protease inhibitor
E1C0K1 Extracellular fatty acid-binding protein ExFABP 1742 4.94 No Fatty acid and bacterial siderophores binding
F1NG13 Transglutaminase 3 TGM3 1572 19.94 No Transglutaminase
Q2IAL7 Cathelicidin 2 CATHL2 1402 7.49 Decrease Antimicrobial peptide
P27042 Lysozyme G LYG2 989 4.57 Decrease Antimicrobial peptide
Q2IAL6 Cathelicidin 3 CATHL3 936 5.37 No Antimicrobial peptide
P00698 Lysozyme C LYZ 839 5.17 Decrease Antimicrobial peptide
Q6QLQ5 Cathelicidin 1 CATHL1 833 4.62 Decrease Antimicrobial peptide
E1BTH1 Leukocyte elastase inhibitor SERPINB1 627 Only Het Decrease Protection against own proteases
F1P284 Leukotriene A(4) hydrolase LTA4H 603 5.78 Decrease Epoxide hydrolase and aminopeptidase
F1NGT3 Matrix metallopeptidase 9 MMP9 600 Only Het Decrease Degradation of the extracellular matrix
F2Z4L6 Serum albumin ALB 557 4.79 Decrease Plasma carrier
P30374 Ribonuclease homolog RSFR 548 6.89 Decrease Lysosomal cysteine protease
R9PXN7 Hematopoietic prostaglandin D synthase HPGDS 504 17.79 No Cytosolic glutathione S-transferases
E1BTV1 Stomatin STOM 502 23.82 No Integral membrane protein
D2D3P4 Rab27a Rab27a 435 88.08 No Small GTPase, exocytosis
R4GI24 Integrin alpha-D ITGAD 379 7.73 No Adhesion of leukocytes
  1. aThe difference in PSM counts of particular protein in Het and Ma.