Table 2 AI virus antigen immunohistochemical staining in tissues from Pekin ducks and Chinese geese inoculated by the intrachoanal route or contact-exposed to H5N8 and H5N2 HPAI viruses
Species | Virus | Detection of AI virus antigen in tissues | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nasal ep. | Trachea | Lung | Air sacs | Brain | Heart | Spleen | Liver | Skeletal muscle | Pancreas | Cloacal bursa | Cecal tonsils | Harderian gland | Thymus | ||
Pekin ducks 4 dpi | H5N8 | ++/+ | +/++ | +/++ | +++/+ | +/+ | +/+ | ++/+ | −/− | +/+ | −/− | +/− | −/− | ++/++ | −/− |
H5N2 | +/+ | +/+ | +/− | +/+ | −/+ | −/− | −/− | −/− | +/− | −/− | +/− | −/− | −/− | +/− | |
Chinese geese 4 dpi | H5N8 | +/++ | +/− | ++/+ | +/− | +/+ | +/++ | ++/+ | −/− | +/− | −/− | −/− | −/− | −/+++ | −/+ |
H5N2 | ++/++ | +/+ | ++/++ | +/na | ++/++ | ++/+++ | ++/++ | +/+ | +/− | +/+ | +/++ | ++/++ | −/− | ++/+ | |
Chinese geese 8 and 10 dpi | H5N2 | +/+ | +/+ | ++/++ | na/na | +++/+++ | ++/++ | ++/+ | +/+ | +/+ | +/+ | +/++ | +/+ | na/na | +/− |