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Table 1 Mortality, number of birds infected, 50% bird infectious doses, and seroconversion of 2-week-old Pekin ducks and Chinese geese inoculated by the intrachoanal route and contact-exposed to A/gyrfalcon/WA/40188-6/2014 (H5N8) and A/Northern pintail/WA/40964/2014 (H5N2) HPAI viruses

From: Infectivity, transmission and pathogenicity of H5 highly pathogenic avian influenza clade 2.3.4.4 (H5N8 and H5N2) United States index viruses in Pekin ducks and Chinese geese

Species

Virus

Inoculated birds

Contact-exposed birds

Virus dose (log10 EID50)

# of infected birds/totala

BID b50 (log10 EID50)

Mortalityc (dpid)

Serologyd (range of antibody titers, log2)

# of infected birds/total

Mortality (dpee)

Serology (range of antibody titers, log2)

Pekin ducks

H5N8

2

0/5

3.0

0/5

0/5

0/3

0/3

0/3

4

5/5

0/5

5/5 (4–5)

1/3

0/3

1/3 (4)

6

5/5

0/5

5/5 (4–5)

2/3

0/3

2/3 (4)

H5N2

2

0/5

3.0

0/5

0/5

0/3

0/3

0/3

4

5/5

0/5

5/5 (3)

2/3

0/3

1/3 (3)

6

4/4

0/4

4/4 (3–4)

3/3

0/3

3/3 (3–5)

Chinese geese

H5N8

2

4/4

< 2

0/4

1/4 (4)

2/2

0/2

0/2

4

4/4

0/4

0/4

2/2

0/2

1/2 (3)

6

4/4

0/4

2/4 (3)

2/2

1/2 (11)

0/2

H5N2

2

0/4

3.0

0/4

0/4

0/2

0/2

0/4

4

4/4

0/4

1/4 (3)

2/2

1/2 (10)

0/1

6

4/4

1/4 (8)

1/3 (3)

2/2

0/2

0/2

  1. aNumber of birds infected/total number of birds inoculated; determined by qRRT-PCR and serology.
  2. bBID50, mean bird infectious dose.
  3. cNumber of dead birds/total number of birds inoculated (days post-inoculation).
  4. dNumber of birds with positive antibody titers/total number of birds inoculated.
  5. eDays post-exposure.