Figure 5
From: Phylodynamics of foot-and-mouth disease virus O/PanAsia in Vietnam 2010–2014
Site selection (dN-dS) by VP1 coding region in alignments of FMDV sequences. A Site selection (dN-dS) results per VP1 coding region in alignments of cattle viral sequences (excluding persistently infected), buffalo (excluding persistently infected) and pigs. Values >0 represent positive selection. Bars colored in red indicate sites where selection is statistically significant. Grey shaded areas correspond to known antigenic sites within VP1: BC loop (sites 43–45), GH loop (sites 238–254), and C terminus (sites 200–207). Pink-shaded sites correspond to the RGD integrin-binding motif. B Site selection (dN-dS) results per VP1 coding region in alignments including of all viral sequences, “clinical” (cattle and buffalo) viral sequences and “carrier” (cattle and buffalo) infected animals.