Figure 5

Genetic organization of upregulated gene locus. A BAB_RS17405 encodes a dihydropyrimidinase on chromosome I of B. abortus S2308. It is flanked by a zinc-dependent allantoate amidohydrolase (BAB_RS17410) and a dihydrorhizobitoxine desaturase (BAB_RS17400). B BAB_RS17430 encodes the α-subunit of NADPH dependent glutamate synthase on chromosome I of B. abortus S2308, downstream of β-subunit B of NADPH dependent glutamate synthase (BAB_RS17425). C BAB_RS24460 encodes a substrate-binding protein on chromosome I of B. abortus S2308. It is flanked by genes for two hypothetical proteins without complete coding sequences (BAB_RS24465 and 24470), an ATP-binding protein with ATPase enzymatic activity (BAB_RS24475), two permease proteins (BAB_RS24480 and 24485) and another substrate-binding protein (BAB_RS24455). D BAB_RS30485 encodes a substrate binding protein which is located on chromosome II of B. abortus S2308. It is flanked by two permease proteins (BAB_RS30470 and 30475) and another ATP-binding protein (BAB_RS30480). Both ABC transporters are predicted to be involved in amino acid transport and metabolism. E BAB_RS27765 encodes a putative fumarylacetoacetate (Faa) hydrolase without known function. It is on chromosome II of B. abortus S2308, upstream of a gene for galactose 1-dehydrogenase (BAB_RS27770). F BAB_RS31735 encodes a putative amidohydrolase without known function. It is on chromosome II of B. abortus S2308, downstream of a gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase (BAB_RS31730) gene. Arrows indicate direction of CDS. Except BAB_RS27765 and 31735, all other CDSs are on the complementary strand of the B. abortus S2308 genome. Tags of upregulated genes are indicated by a darker color.