Genotyping and investigating capsular polysaccharide synthesis gene loci of non-serotypeable Streptococcus suis isolated from diseased pigs in Canada

Zheng, Han; Qiu, Xiaotong; Roy, David; Segura, Mariela; Du, Pengchen; Xu, Jianguo; Gottschalk, Marcelo

doi:10.1186/s13567-017-0417-6

Veterinary Research

Table 2 Mutations in glycosyltransferase, side-chain formation, wzy and wzx genes of serotype 2 or 1/2 representative strains and a serotype 27 strain

From: Genotyping and investigating capsular polysaccharide synthesis gene loci of non-serotypeable Streptococcus suis isolated from diseased pigs in Canada

Strain	Affected gene(s)	Types of mutations	Affected nucleotide(s) [Affected amino acid]
1827702	cps2E	Missense	A61G [Thr21Ala]
	cps2I	Insertion	IS element: 33 bp
	cps2N	Deletion	27 bp
1090772	cps2E	Missense	A61G [Thr21Ala]
	cps2F	Missense	A149G [Asp50Gly]
		Missense	A1047T [Leu349Phe]
	cps2I	Insertion	IS element: 33 bp
	cps2N	Deletion	27 bp
	cps2O	Missense	C859A [Arg287Ser]
1160406	cps27E	Missense	A506G [Asp169Gly]
		Missense	T508A [Ser170Thr]
		Missense	A513T [Glu171Asp]
		Missense	A522T [Lys174Asn]
		Missense	A524T A525T [Lys175Ile]
		Missense	A541C C543G [Ile181Leu]
		Missense	A553G [Ile185Val]
		Missense	G617T T618G [Ser206Met]
		Missense	A623T [Tyr208Phe]
		Missense	T633G [Leu211Val]
		Missense	C640T A642C [Leu214Phe]
		Missense	A651T [Glu217Asp]
		Missense	C692T [Ser231Leu]
		Missense	G706A A708G [Ala236Thr]
		Missense	G874A A876T [Val292Ile]
		Missense	T905C [Val302Ala]
		Missense	A922C A924G [Lys308Gln]
		Missense	A941C G942A [Lys314Thr]
		Missense	A967G [Ile323Val]
		Missense	A997C G999C [Met333Leu]
		Missense	G1000A C1001G T1002C [Ala334Ser]
		Missense	A1174C A1175G [Lys392Arg]
		Missense	G1186A G1187T T1188G [Gly396Met]
		Missense	A1272C [Glu424Asp]
		Missense	A1279C A1280G [Lys427Arg]
		Missense	G1288T T1290A [Val430Leu]
		Missense	A1292C [Glu431Ala]
		Missense	G1324A A1326T [Val442Ile]
		Missense	A1357T T1359G [Ile453Leu]
		Missense	A1360T A1361T [Lys454Leu]
	cps27F	Deletion	27 bp
		Missense	A662T [His221Leu]
	cps27G	Insertion	IS element: 21 bp
	cps27I	Missense	G483C [Trp161Cys]
		Missense	C513A [Asp171Glu]
		Missense	A611G [Gln204Arg]
	cps27L	Deletion	57 bp
	cps27M	Missense	C1373T C1374T [Ala458Val]
		Missense	C1375T [Leu459Phe]

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ISSN: 1297-9716

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