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Table 3 mRNA expression of genes involved in the type I interferon response of common carp

From: Experimental infections of different carp strains with the carp edema virus (CEV) give insights into the infection biology of the virus and indicate possible solutions to problems caused by koi sleepy disease (KSD) in carp aquaculture

Carp strain

CEV genogroup I

CEV genogroup IIa

Control

Day 6

Day 11

Control

Day 6

Day 11

Cyca IFN a2

 Koi

  Mean

6.1E+01 a

1.9E+02 a

1.4E+02 a

6.1E+01 a

1.8E+02 a

8.4E+02 b*

  SD

3.3E+01

1.2E+02

9.5E+01

3.3E+01

1.0E+02

1.9E+02

  PS

  Mean

6.6E+01 a

1.5E+02 a

1.2E+02 a

6.6E+01 a

1.2E+02 a

9.5E+01 a

  SD

7.5E+00

2.4E+01

7.1E+01

7.5E+00

4.9E+01

3.3E+01

 Rop

  Mean

7.9E+01 a

1.3E+02 ab

9.6E+01 ab

7.9E+01 a

9.3E+01 a

8.5E+01 a

  SD

4.1E+01

4.3E+01

4.2E+01

4.1E+01

4.0E+01

4.4E+01

 AS

  Mean

1.6E+02 a

4.8E+01 b*

3.8E+01 b*

1.6E+02 a

1.2E+02 a

1.2E+02 a

  SD

1.2E+02

1.9E+01

1.8E+01

1.2E+02

4.7E+01

4.2E+01

Cyca Viperin

 Koi

  Mean

7.3E+02 a

4.2E+04 a*

3.6E+04 a*

7.3E+02 a

3.1E+04 a*

2.5E+04 a*

  SD

3.2E+02

1.5E+04

2.1E+04

3.2E+02

1.0E+04

5.3E+03

 PS

  Mean

9.0E+02 a

3.8E+04 a*

2.7E+04 ab*

9.0E+02 a

9.4E+03 b*

3.6E+03 b*

  SD

2.6E+02

2.6E+03

1.3E+04

2.6E+02

4.4E+03

1.2E+03

 Rop

  Mean

9.0E+02 a

2.3E+04 a*

1.2E+04 ab*

9.0E+02 a

1.5E+04 ab*

4.0E+03 b*

  SD

6.7E+02

1.8E+04

1.0E+04

6.7E+02

1.9E+03

2.8E+03

 AS

  Mean

2.2E+03 a

6.3E+03 b*

7.7E+03 b*

2.2E+03 a

7.0E+03 b*

1.4E+03 b*

  SD

2.9E+03

5.2E+03

4.0E+03

2.9E+03

1.6E+03

2.4E+02

Cyca PKR

 Koi

  Mean

3.6E+02 a

5.6E+03 ab*

4.5E+03 ab*

3.6E+02 a

5.4E+03 a*

4.8E+03 a*

  SD

8.4E+01

9.8E+02

2.2E+03

8.4E+01

1.6E+03

1.1E+03

 PS

  Mean

7.3E+02 a

7.5E+03 a*

4.9E+03 a*

7.3E+02 a

3.1E+03 ab*

1.1E+03 bc*

  SD

1.2E+02

7.6E+02

5.0E+02

1.2E+02

1.6E+03

2.1E+02

 Rop

  Mean

9.3E+02 a

3.6E+03 bc*

2.6E+03 ab*

9.3E+02 a

4.7E+03 a*

1.7E+03 b*

  SD

2.2E+02

1.3E+03

1.2E+03

2.2E+02

9.4E+02

1.0E+03

 AS

  Mean

7.4E+02 a

2.0E+03 c*

1.9E+03 b*

7.4E+02 a

2.0E+03 b*

6.5E+02 c*

  SD

5.8E+02

1.0E+03

7.2E+02

5.8E+02

5.0E+02

1.1E+02

  1. Expression levels of genes encoding for common carp Cyprinus carpio (Cyca) virus-induced interferon a2 (Cyca IFN a2), the interferon induced proteins viperin (Cyca Viperin), and RNA dependent protein kinase (Cyca PKR) were measured in the gills during infection with carp edema virus from the genogroup I or genogroup IIa. Expression levels are shown as means and standard deviations (SD) of the copy number of mRNA encoding the gene normalised against 100 000 copies of the common carp 40S ribosomal protein S11 from n = 4 fish. Symbol “*” indicates significant differences at p ≤ 0.05 between infected and control individuals. Different letters indicate significant differences at p ≤ 0.05 between carp strains.
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Veterinary Research

ISSN: 1297-9716