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Figure 1 | Veterinary Research

Figure 1

From: Frequency of Th17 cells correlates with the presence of lung lesions in pigs chronically infected with Actinobacillus pleuropneumoniae

Figure 1

Microbiological investigation, lung pathology, clinical signs and antibody titers of APP-infected pigs. A The presence of APP was investigated at different host locations during necropsy (GM, Glandula mandibularis; TBLN, tracheobronchial lymph node; BALF, bronchoalveolar lavage fluid). Red boxes indicate APP detection by agar isolation, orange boxes indicate APP detection by PCR and orange boxes with red lines indicate positive results by both techniques. Green boxes indicate negative findings for APP. Results shown in the table refer to sampling on the day of euthanasia. The nasal swabs of animals #11, 9, 12, 16 and 17 were tested positive only on day 14 and/or 21 pi. This is indicated by red boxes with §. B Pathology of the lung was assessed by lung lesion score (LLS) for the lung tissue and by slaughterhouse pleurisy evaluation system (SPES) for the pleura. C Rectal temperatures were measured daily in both infected (colored lines) and control (black lines) animals. Body temperature of 40 °C or higher was considered as fever (red line). D Humoral response against APP serotype 2. Data are expressed as a ratio between optical density of the sample (ODs) and the mean of the optical density of the positive control (MODp). Colored lines in the left graph show ratios for infected animals, black lines in the right graph indicate ratios from sera of control animals.

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