Increased frequency of porcine epidemic diarrhea virus shedding and lesions in suckling pigs compared to nursery pigs and protective immunity in nursery pigs after homologous re-challenge

Table 3 Severity of microscopic lesions and presence of PEDV antigen determined by IHC in tissues from pigs infected with PEDV at 8 weeks of age

Segment^a	dpi 1		dpi 2		dpi 3		dpi 14
Segment^a	Lesions^b	PEDV^c	Lesions	PEDV	Lesions	PEDV	Lesions	PEDV
Duodenum	0/5	0/5	0/3	1/3 (3, 1)^d	13/20 (2, 1)	15/20 (3, 2.3)	0/30	0/30
Ileum	0/5	0/5	0/3	1/3 (3, 1)	13/20 (3, 2)	15/20 (3, 3)	0/30	0/30
Jejunum	0/5	0/5	0/3	1/3 (1, 0.3)	13/20 (3, 3)	15/20 (3, 3)	0/30	0/30
Colon	0/5	0/5	0/3	0	0/20	6/20 (1, 0.3)	0/30	0/30
Mesenteric lymph node	0/5	0/5	0/3	0/3	0/20	12/20 (2, 1)	0/30	0/30

^aThree sections were collected and evaluated for each intestinal segment.
^bMicroscopic lesions included villous atrophy and lymphocytic inflammation and were scored as 0 = absent to 3 = severe.
^cPrevalence and amount of PEDV antigen were scored as 0 = absent to 3 = abundant for each intestinal segment.
^dThe average score of three sections of each segment was calculated as the segment score. Data presented as prevalence (highest score in a segment, median segment score).

ISSN: 1297-9716