Table 1 Summary of inoculation outcomes with survival times and rates
From: L-BSE experimentally transmitted to sheep presents as a unique disease phenotype
Passage | Recipient genotype | No positive/challenged | Individual survival times (dpi) for positive sheep | Mean ip (±SD) of clinically positive sheep | Mean survival times (+SD) of negative sheep |
|---|---|---|---|---|---|
Primary | VRQ/VRQ | 4/5 | 1183, 1337, 1439,1963a, | 1320 ± 129 | 1964 |
|  | VRQ/ARQ | 5/5 | 803b, 864, 957, 1056, 1389 | 1014 ± 231 |  |
|  | ARQ/ARQ | 5/5 | 956, 959, 1186, 1531, 1649 | 1256 ± 321 |  |
|  | AFRQ/AFRQ | 4/5 | 1186b, 1236, 1267, 1334 | 1256 ± 62 | 867c |
|  | ARR/ARR | 0/5 |  |  | 2001 ± 3 |
Subpassage: Donor ARQ/VRQ | ARQ/VRQ | 5/5 | 433, 454, 462, 478, 478 | 461 ± 19 |  |
|  | AFRQ/AFRQ | 5/5 | 503, 505, 527, 552, 552 | 528 ± 24 |  |
Subpassage:Donor AFRQ/AFRQ | ARQ/VRQ | 5/5 | 461, 488, 496, 501, 531 | 495 ± 25 |  |
|  | AFRQ/AFRQ | 5/5 | 473, 519, 520, 520, 539 | 514 ± 25 |  |