Diagram showing PK resistance of PrP
from Cypriot goats as compared to BSE controls. Proteinase K-resistance of PrPSc after 1, 6, 24 and 48 h digestion, showing the higher susceptibility of the different scrapie cases (ZYP13, ZYP19, ZYP21, ZYP27, ZYP30) compared to ovine (486) and caprine BSE (ZG01). The signal of the PrPSc in the western blot is shown as a percentage of the overall signal after 1 h (=100%). The data are obtained by four gel runs (ZYP21 = three gel runs).