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Table 2 Summary of post mortem findings

From: Vaccination sequence effects on immunological response and tissue bacterial burden in paratuberculosis infection in a rabbit model

Group Animal Gross pathologya Tissue qPCR GE/g Tissue culture
SR VA MUC SR VA MUC SR VA ICV.IL MLN
  ST
NIC 0
1
2
3 ++ ++ + 246 42.9 86.7 + + + +
IC 4 + ++ + 5.13 + +
  5 + + 620
6 + + + 37.8 + +
7 + + 200 105 6.27 +
8
IVS 9 ++
10 + 1130
12
13 1690 38.4
19 258 2.45 +
VSI 20 NA 7.16
23 + +
24
  1. NIC: non infected control, IC: infected control, IVS: infected before vaccination, VSI: vaccinated before infection, SR: sacculus rotundus, VA: vermiform appendix, MUC: ileum and jejunum mucosa, ICV.IL: ileocecal valve and Ileum, MLN: mesenteric lymph node, NA: not analyzed.
  2. aGross pathology consisting of the following: pale white reactive spots and severe wall thickening (++) and increased vascularity and mild wall thickening (+).