Productive replication of nephropathogenic infectious bronchitis virus in peripheral blood monocytic cells, a strategy for viral dissemination and kidney infection in chickens

Table 1 Experimental design of in vivo IBV (B1648/M41) infection study

Group	Number of animals	Time of inoculation (days post inoculation)
Virus strain	Number of animals	Observation of clinical signs	Tracheal swab collection	Blood collection (plasma and PBMC^a)	Euthanasia
B1648	3	−3 to 12	0, 2, 4, 6, 8, 10, 12	0, 2, 4, 6, 8, 10, 12	12
M41	3	−3 to 12	0, 2, 4, 6, 8, 10, 12	0, 2, 4, 6, 8, 10, 12	12
PBS control	3	−3 to 12	0, 2, 4, 6, 8, 10, 12	0, 2, 4, 6, 8, 10, 12	12

ISSN: 1297-9716